A loss would mean the Reds fall out of the top 4, and so a win is an absolute must for Klopp's side.
Roberto Firmino (hamstring), Joe Gomez (calf), Curtis Jones (eye), Naby Keita (hamstring) and James Milner (hamstring) are all ruled out for the Gunners’ visit while Jordan Henderson and Andy Robertson are likely out too.
Having considered that, which players should Jurgen Klopp choose to get the best result against Arsenal?
Option 1: Strongest XI
This game promises to be a tough one and Liverpool will need their best players to step up if they are to grab a victory.
The best available players based on the whole season should play, with Tsimikas slotting in as well as Joel Matip retaining his spot alongside Virgil van Dijk.
Fabinho would be joined in midfield by Thiago and the lately impressive Alex Oxlade-Chamberlain.
LFC XI: Alisson, Alexander-Arnold, Matip, Van Dijk, Tsimikas, Fabinho, Oxlade-Chamberlain, Thiago, Mane, Jota, Salah
Option 2: Neco, Konate in
Neco Williams was incredibly impressive for Wales during the international break down the left side, and could be considered for this game.
Neco starting down the left and the youth and power of Ibrahima Konate through the middle could be just the refresher the Reds' defence needs.
In attack Takumi Minamino could feature as the link between midfield and attack, adding extra firepower for Klopp's side.
LFC XI: Alisson, Alexander-Arnold, Van Dijk, Konate, N. Williams, Fabinho, Thiago, Minamino, Mane, Jota, Salah
Which starting XI would you like to see take the field?
