Team news
Sevilla
- The Andalusians will miss first-choice left-back Marcos Acuna, first-choice right-back Jesus Navas, back-up central midfielder Oscar Rodriguez and first-choice left winger Lucas Ocampos through injuries.
Barcelona
- Barcelona won't be able to count on Ronald Araujo, Gerard Pique, Sergino Dest, Sergi Roberto, Miralem Pjanic, Philippe Coutinho, Ansu Fati and Martin Braithwaite through injuries.
Key stats
- Sevilla have won 9 of their 11 games in 2021.
- Barcelona are unbeaten away from home since December 5.
- Barca have won just 3 of their last 6 games against Sevilla in all competitions.
Possible line-ups
Barcelona XI: Ter Stegen; Mingueza, Lenglet, Umtiti, Alba; Busquets, De Jong; Messi, Pedri, Dembele; Griezmann.
Sevilla XI: Bounou; Navas, Kounde, Carlos, Rekik; Jordan, Fernando, Rakitic; Suso, En-Nesyri, Ocampos. (h/t SportsMole)
Manager quotes
Julen Lopetegui (Sevilla): "Barca are a great team, plus they have Messi. They are a very remarkable team in all aspects and they are doing a good job these days. While respecting the rival, we focus on ourselves, of course." (h/t Mundo Deportivo)
Ronald Koeman (Barcelona): "It's a two-legged clash and for us, it's important to get a good result tomorrow. We know them [Sevilla] well and it will be a great game."
Predictions
SportsMole's Daniel Lewis: Sevilla 1-1 Barcelona
"Sevilla have won seven games in a row and Barcelona have won six on the spin, so something has to give at the Estadio Ramon Sanchez Pizjuan on Wednesday evening.
"The last two meetings between the sides have finished all square and we are backing this one to finish the same way, setting up a tasty second leg at Camp Nou in early March."