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Declan Rice appears to have picked up an injury during Arsenal's 5-0 thrashing of Crystal Palace.
Shortly before Jorginho replaced him, the Englishman was heard saying "hammy" which may imply a hamstring injury.
Rice has started all of Arsenal's Premier League games after joining from West Ham in the summer. He hasn't missed any Champions League matches either.
His injury will be a major headache for Mikel Arteta who is already short of options in midfield.
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